We have located links that may give you full text access.
Interplay Between Cognitive and Bowel/Bladder Function in Multiple Sclerosis.
International Neurourology Journal 2021 May 7
Purpose: to evaluate the prevalence of bowel/bladder dysfunction in multiple sclerosis (MS) and the association with cognitive impairment.
Methods: We prospectively enrolled 150 MS patients. Patients were administered the Symbol Digit Modality Test (SDMT), and filled the Neurogenic Bowel Dysfunction Score (NBDS) and the Actionable Bladder Symptom Screening Tool (ABSST). Association between bowel/bladder dysfunction and cognitive function was assessed through hierarchical regression models using SDMT and clinic-demographic features as independent variables and NBDS or ABSST score as dependent variables.
Results: Prevalence for bowel/bladder deficit was 44.7%, with 26 patients (17.3%) suffering from bowel deficits and 60 patients (40%) from bladder deficits. Total NBDS and ABSST correlated with SDMT (coeff. = -0.10, p<0.001 and coeff. = -0.03, p=0.04, respectively) after correction for demographic features and physical disability.
Conclusions: Bowel/bladder disorders are common in MS and are associated with both physical and cognitive disability burden. As SDMT is embedded into routine clinical assessment, a lower score may warrant investigating bowel/bladder dysfunction due their strong interplay.
Methods: We prospectively enrolled 150 MS patients. Patients were administered the Symbol Digit Modality Test (SDMT), and filled the Neurogenic Bowel Dysfunction Score (NBDS) and the Actionable Bladder Symptom Screening Tool (ABSST). Association between bowel/bladder dysfunction and cognitive function was assessed through hierarchical regression models using SDMT and clinic-demographic features as independent variables and NBDS or ABSST score as dependent variables.
Results: Prevalence for bowel/bladder deficit was 44.7%, with 26 patients (17.3%) suffering from bowel deficits and 60 patients (40%) from bladder deficits. Total NBDS and ABSST correlated with SDMT (coeff. = -0.10, p<0.001 and coeff. = -0.03, p=0.04, respectively) after correction for demographic features and physical disability.
Conclusions: Bowel/bladder disorders are common in MS and are associated with both physical and cognitive disability burden. As SDMT is embedded into routine clinical assessment, a lower score may warrant investigating bowel/bladder dysfunction due their strong interplay.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app