Adalimumab in the Management of Isotretinoin-Induced Acne Fulminans: Report of a Case

Claudio Marasca, Gabriella Fabbrocini, Luisa Abategiovanni, Elisa Camela, Mariateresa Nocerino, Adriana Di Guida, Gaia De Fata Salvatores
Skin Appendage Disorders 2021, 7 (2): 115-119
Acne fulminans (AF) is a rare, acute, and severe form of acne vulgaris often associated with systemic symptoms. Its treatment is challenging and controversial. We report a case of isotretinoin-induced AF (IIAF) in a 12-year-old boy resistant to traditional therapies (oral steroids and isotretinoin). The patient was successfully treated with adalimumab that can be considered an effective off-label option in the treatment of resistant IIAF in children.

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