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Acute digital necrosis due to interferon-α-induced ANCA-associated vasculitis.
Arthritis & Rheumatology 2021 Februrary 19
A 69-year-old woman, whose HTLV-1 associated myelopathy (HAM) had been treated with interferon-α (IFN), presented with a three-week history of high fever, rapidly progressive discoloration and pain in the digits. Physical examination revealed black discoloration of the distal right second and fifth distal fingers (Figure 1A and B), and left second through fifth distal fingers, and purpuric lesions on several fingers.
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