The Association Between Urinary BPA Levels and Medical Equipment Among Pediatric Intensive Care Patients

Ganime Ayar, Sıddıka Songül Yalçın, Serhat Emeksiz, Anıl Yırün, Aylin Balcı, Belma Kocer-Gumusel, Pınar Erkekoğlu
Environmental Toxicology and Pharmacology 2021 January 15, : 103585
We aim to evaluate urinary total BPA (tBPA) levels and association with medical devices used on patients in pediatric intensive care units. This cross-sectional descriptive study included 117 critically ill children. Urinary tBPA levels were determined using high-performance liquid chromatography. General estimating equations with repeated measures analyzed the effect of interventions and devices on urinary BPA levels. A total of 292 urine samples taken from 117 child intensive care patients were studied. When age, sex, and body mass index-for age z-scores were controlled, cases having endotracheal intubation showed higher urinary tBPA levels (p = 0.003) and hemodialyzed patients had considerably higher urinary tBPA levels (p = 0.004). When confounding factors were controlled, cases using both multiple iv treatment and more than four medical devices showed higher urinary tBPA levels than their counterparts (p = 0.007 and p = 0.028, respectively). The use of certain medical devices and interventions could increase BPA exposure in pediatric intensive care patients.

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