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A Crisp(r) New Perspective on SARS-CoV-2 Biology.

Adam L Bailey, Michael S Diamond
Cell 2021 January 8
Complementary genome-wide CRISPR-Cas9 screens performed by multiple groups reveal new insights into SARS-CoV-2 biology including aspects of viral entry, translation, replication, egress, and the genes regulating these processes. Comparisons with other coronaviruses enhances our understanding of the cellular life cycle of this medically important family of emerging viruses.

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