Add like
Add dislike
Add to saved papers

Understanding the Role of Corona Virus based on Current Scientific Evidence - a Review with Emerging Important in Pandemic.

Coronavirus disease is a potentially deadly disease and of significant apprehension for global communal health potentially because of its lethality. Vaccines and antiviral medications are still under trial to prevent or treat infections of human coronavirus (HCoV) till date. The virus HCoV originate in 2003, SARS-CoV, which causes respiratory syndrome having distinctive pathogenesis and causes infections of the respiratory tract. A mechanism was projected for the evolution of SARS virus and a handy association with bats was found. When this virus reaches respective host system, infection starts with spike protein binding to its complementary receptor of the host cell. The coronavirus spike protein's association with its host cell receptor complement is crucial in deciding the virus infectivity, tissue tropism and species variety. Recent studies show that SARS Coronavirus 2 or COVID-19 requires protease to get into cells, offering a new therapeutic target. Distinctive attention and exertions should be given to defending or reducing transmission in vulnerable populaces, including those directly associated with caregiving and treatment and also aged one. Researchers are planning to develop a vaccine for COVID-19 and in this approach are also considered developing a vaccine that sensitizes our immune system preventing from this pandemic. The present review focuses on the role of S-spike protein in COVID-19 which helps the virus intruder the enzyme ACE2 (angiotensin-converting enzyme 2). Passive antibody therapy is an additional alternate that purposes to use blood donors from hale and hearty people who have already recovered from COVID-19 and therapeutic advancement in handling COVID-19 pandemic.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app