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Second to fourth digit ratio (2D:4D) is associated with dementia in women.
Early Human Development 2020 October
Alzheimer's disease is characterized by sex differences that may involve sex hormone exposure during development. Finger length ratios, an indirect measure of prenatal androgen exposure, were found to significantly differ in women with and without dementia. This finding links a relatively feminine in utero development with vulnerability to dementia in women.
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