A Comparative assessment of Metabolic Syndrome and its association with Vitamin D and other risk factors in Type 2 Diabetes Mellitus Patients.

OBJECTIVES: To determine the overall prevalence of metabolic syndrome using World health organization (WHO); National Cholesterol Education program (NCEP) and International diabetes federation (IDF) guidelines and to study its association with vitamin D and other biochemical parameters in patients with type 2 Diabetes mellitus, as well as to identify the set of biochemical parameters that jointly influence the metabolic syndrome using different diagnostic criteria.

METHODS: A cross-sectional study was carried out at private health care center. A total of 291 diabetic patients. Sociodemographic, clinical, and laboratory data were obtained from the medical records of patients. Statistical analysis was carried out using the Statistical Package for the Social Sciences (SPSS, version 23).

RESULTS: A total number of 291 patients with T2DM were included in this study. The overall prevalence of metabolic syndrome among the study subjects was 48.1%, 87.3%, 64.9% using WHO, IDF and NCEP-ATPIII criteria respectively. The highest prevalence was reported following IDF diagnostic criteria. Sex, triglyceride and fasting blood sugar were associated factors of metabolic syndrome by all the three diagnostic criteria of metabolic syndrome.

CONCLUSION: the study revealed high prevalence rate of metabolic syndrome among type 2 diabetic patients, which was highest 87.3% according to IDF and lowest was observed in WHO criteria 48.1%. A significant variance in the prevalence of metabolic syndrome was reported between WHO, IDF and NCEP criteria.