The effectiveness of L-PRF in the treatment of Schneiderian membrane large perforations: long-term follow-up of a case series

Carolina Mendonça de Almeida Malzoni, Lelis Gustavo Nicoli, Gustavo da Col Dos Santos Pinto, Claudio Marcantonio, Suzana Cristina Pigossi, Vinicius Aparecido Zotesso, Mario Henrique Arruda Verzola, Victor Gonçalves, Elcio Marcantonio, Daniela Leal Zandim-Barcelos
Journal of Oral Implantology 2020 July 13
The perforation of the Schneiderian membrane (SM) is a common surgical complication during the sinus floor augmentation procedure (SFA). Different approaches have been proposed to close completely the SM perforation and to avoid graft contamination or migration and postoperative sinus infection. In this context, the leukocyte and platelet-rich fibrin (L-PRF) membranes have been proposed to SM perforation treatment due to its natural adhesive property and resistance. Thus, these case series aim to evaluate the effectiveness of platelet rich fibrin (L-PRF) in the treatment of SM large perforations during SFA. A total of 9 SM perforation was treated in this case series. The L-PRF membranes were interposed on the perforated SM until the rupture could not be visualized. The maxillary sinus cavities were filled with deproteinized bovine mineral bone (Bio-oss®, Geistlich, Switzerland) and a collagen membrane was positioned to cover the lateral access window. After 8 months, 13 implants were placed achieving satisfactory primary stability. The osseointegration of all implants and absence of infection signs/mucus in the maxillary sinus were observed in cone beam computed tomography or panoramic radiography qualitative analysis after 3-5 years of follow-up. It can be concluded that the use of L-PRF can be considered a viable alternative for the repair of large SM perforations.

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