Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019.

Carolina Garcia-Vidal, Estela Moreno-García, Marta Hernández-Meneses, Pedro Puerta-Alcalde, Mariana Chumbita, Nicole Garcia-Pouton, Laura Linares, Verónica Rico, Celia Cardozo, José Antonio Martínez, Felipe García, Josep Mensa, Pedro Castro, José María Nicolás, José Muñoz, David Vidal, Alex Soriano

Clinical Infectious Diseases 2022 January 8

Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR] .144; 95% confidence interval [CI] .03-.686; P = .015). Increasing age (OR 1.06; P = .038) and therapeutic effort limitation (OR 9.684; P < .001) were associated with higher mortality.

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