Incidental primary breast cancer detected on surveillance 68 Ga-DOTATATE PET/CT in a patient with metastatic neuroendocrine carcinoma

Emily B Ambinder, Rudolf A Werner, Steven P Rowe
Radiology Case Reports 2020, 15 (8): 1344-1347
32617128
We present a case of a 53-year-old woman with metastatic neuroendocrine tumor, presumed primary in the small intestine with metastases to the liver and mesenteric lymph nodes. The patient was being treated with lanreotide and followed with somatostatin receptor (SSTR)-targeted 68Ga-labeled 1,4,7,10-tetraazacyclododecane- N,N ', N '', N '''-tetraacetic acid-d-Phe(1)-Tyr(3)-octreotate (68 Ga-DOTATATE) positron emission tomography - computed tomography (PET/CT). On a follow-up exam, the patient's primary and metastatic disease had improved but she had new 68 Ga-DOTATATE-avid lesions in the right breast and right axilla. Subsequent breast imaging workup and biopsy demonstrated a primary breast cancer and axillary lymph node metastasis.

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