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LETTER

Antacid Monotherapy Is More Effective in Relieving Epigastric Pain Than in Combination With Lidocaine: A Randomized Double-blind Clinical Trial

Jaimee Warren, Blake Cooper, Anton Jermakoff, Jonathan C Knott

Academic Emergency Medicine 2020, 27 (9): 905-909

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The GI Cocktail is no more effective than plain liquid antacid: a randomized, double blind clinical trial. Dean A Berman, Robert S Porter, Mylissa Graber Journal of Emergency Medicine 2003, 25 (3): 239-44

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Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial. Terence T Sio, Jennifer G Le-Rademacher, James L Leenstra, Charles L Loprinzi, Grant Rine, Amarinthia Curtis, Anurag K Singh, James A Martenson, Paul J Novotny, Angelina D Tan, Rui Qin, Stephen J Ko, Paul L Reiter, Robert C Miller JAMA 2019 April 16, 321 (15): 1481-1490

Does lidocaine as an adjuvant to morphine improve pain relief in patients presenting to the ED with acute renal colic? A double-blind, randomized controlled trial. Abolfazl Firouzian, Abbas Alipour, Hale Rashidian Dezfouli, Alieh Zamani Kiasari, Afshin Gholipour Baradari, Amir Emami Zeydi, Hamed Amini Ahidashti, Maryam Montazami, Seyed Mohammad Hosseininejad, Farideh Yazdani Kochuei American Journal of Emergency Medicine 2016, 34 (3): 443-8

Treatment with cimetidine, antacid, or placebo in patients with dyspepsia of unknown origin. R Gotthard, G Bodemar, U Brodin, K A Jönsson Scandinavian Journal of Gastroenterology 1988, 23 (1): 7-18

Relief of epigastric pain in nonulcer dyspepsia: controlled trial of the promotility drug cisapride. N De Nutte, W Van Ganse, M Witterhulghe, P Defrance Clinical Therapeutics 1989, 11 (1): 62-8

Randomized clinical trial: rikkunshito in the treatment of functional dyspepsia--a multicenter, double-blind, randomized, placebo-controlled study. H Suzuki, J Matsuzaki, Y Fukushima, F Suzaki, K Kasugai, T Nishizawa, Y Naito, T Hayakawa, T Kamiya, T Andoh, H Yoshida, Y Tokura, H Nagata, M Kobayakawa, M Mori, K Kato, H Hosoda, T Takebayashi, S Miura, N Uemura, T Joh, T Hibi, J Tack Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society 2014, 26 (7): 950-61

Acute relief of epigastric pain by antacid in duodenal ulcer patients. S J Rune, A Zachariassen Scandinavian Journal of Gastroenterology. Supplement 1980, 58: 41-5

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