Nondegenerated cystic neuroendocrine tumor of the pancreas: a case report

Keisuke Noda, Tamotsu Kuroki, Mampei Yamashita, Takanori Hirayama, Koji Natsuda, Shinichiro Kobayashi, Takayuki Tokunaga, Kosho Yamanouchi, Hiroaki Takeshita, Shiro Miura, Shigeto Maeda
Surgical Case Reports 2020 June 29, 6 (1): 154

BACKGROUND: Pancreatic neuroendocrine tumors (PNETs) are typically solid neoplasms but, in very rare cases, present as cystic lesions. We describe a case of a cystic neuroendocrine tumor that developed as a small cystic lesion.

CASE PRESENTATION: In 2011, a 66-year-old Japanese woman underwent computed tomography (CT) that revealed a cystic lesion in the tail of the pancreas measuring 9 mm. She did not have any symptoms. She underwent a CT scan every year thereafter. The cystic lesion gradually increased and was 40 mm in 2019; endoscopic retrograde pancreatography (ERP) was then performed. Cytological examination demonstrated class IIIb adenocarcinoma, and we conducted laparoscopic distal pancreatectomy. Pathological examination showed PNET.

CONCLUSION: Although cystic change of PNET is generally caused by ischemia or necrosis inside the tumor, in our case, PNET occurred as a small cyst that increased without changing form.

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