Add like
Add dislike
Add to saved papers

Beer spoilage and low pH tolerance is linked to manganese homeostasis in selected Lactobacillus brevis strains.

AIMS: Beer is a harsh medium for bacteria to survive, however, lactic acid bacteria (LAB) including Lactobacillus brevis have evolved the ability to grow in beer. Here, the influence of environmental factors such as low pH, ethanol or hop content was assessed.

METHODS AND RESULTS: A transcriptomic analysis of two Lb. brevis beer-spoiling strains was performed comparing growth in nutritive media with or without the imposition of a stressor related to the beer environment. This allowed the identification of a manganese transporter encoding gene that contributes to low pH tolerance.

CONCLUSIONS: We report on the importance of a manganese transporter associated with pH tolerance and beer spoilage in Lb. brevis. The importance of manganese for Lb. brevis growth in a low pH environment was highlighted.

SIGNIFICANCE AND IMPACT OF STUDY: Bacterial spoilage of beer may result in product withdrawal with concomitant economic losses for the brewing industry. A limited number of genes involved in beer spoilage have been identified but none of them are universal. It is clear that other molecular players are involved in beer spoilage. The study highlights the complexity of the genetic requirements to facilitate beer spoilage and the role of multiple key players in this process.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app