JOURNAL ARTICLE

Physiopathological and diagnostic aspects of cirrhotic cardiomyopathy

Talia M Leal-Alvarado, Ignacio Escalante-Sandoval, José L Gálvez-Romero, Paola Ávila-López, José L Flores-Castillo, Montserrat Galván-Ramírez
Archivos de Cardiología de México 2020, 90 (2): 169-177
32459210
Cirrhotic cardiomyopathy is characterized by the presence of structural and functional cardiac alterations in patients suffering from hepatic cirrhosis, without previously known cardiac causes that may explain it. Clinically, it is characterized by the presence of variable grades of diastolic and systolic dysfunction, alterations in the electric conductance (elongation of corrected QT interval) and inadequate chronotropic response. This pathology has been related to substandard response in the management of patients with portal hypertension and poor outcome after transplant. Even when the first description of this pathology dates back from 1953, it remains a poorly studied and frequently underdiagnosed entity. Echocardiography prevails as a practical diagnostic tool for this pathology since simple measurements as the E/A index can show diastolic dysfunction. Systolic dysfunction discloses as a diminished ejection fraction of the left ventricle and the latent forms are detected by echocardiography studies with pharmacological stress. In recent years new techniques such as the longitudinal strain have been studied and they seem promising for the detection of early alterations.

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