We have located links that may give you full text access.
Clinical impact of Controlling Nutritional Status (CONUT) score on the prognosis of patients with diffuse large B-cell lymphoma.
Hematological Oncology 2020 March 30
The Controlling Nutritional Status (CONUT) score is a nutritional index calculated from serum albumin and total cholesterol levels and lymphocyte counts. Its role in predicting clinical outcomes of diffuse large B-cell lymphoma (DLBCL) has not been evaluated. In this retrospective study, data from 476 patients with DLBCL were analyzed. The cutoff value of the CONUT score was set as 4. CONUT score significantly stratified the overall survival (OS) and the progression-free-survival (PFS) (5-year OS, 49.0 % vs. 83.2 %, P < 0.001; 5-year PFS, 46.1 % vs. 73.1 %, P < 0.001.) of the patients. Among patients at high-intermediate or high risk, as per the national comprehensive cancer network international prognostic index (NCCN-IPI), 5-year OS was lower in patients with high CONUT scores than in those with low CONUT scores (high-intermediate risk, 51.2% vs. 75.5%, P < 0.001; high risk, 29.9% vs. 63.3%, P = 0.007). Additionally, in patients with high CONUT scores, maintenance of relative dose intensity (RDI) of chemotherapy did not affect the 5-year OS (RDI > 80% vs. RDI ≤ 80%: 59.8% vs. 50.9%, P = 0.73). In the present study, we have demonstrated that the CONUT score is an independent prognostic factor in patients with DLBCL. This article is protected by copyright. All rights reserved.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app