JOURNAL ARTICLE

The characteristic of tumor immune microenvironment in pulmonary carcinosarcoma

Yanhong Cen, Zhao Huang, Jiangbo Ren, Junhong Zhang, Yan Gong, Conghua Xie
Immunotherapy 2020 March 26
32212951
Pulmonary carcinosarcoma (PCS) is a rare but aggressive neoplasm, due to late diagnosis and early metastasis. Surgery combined with radiotherapy is a standard treatment. However, PCS features an easy relapse after surgery resection and resistance to chemotherapy and radiotherapy. Tumor immune microenvironment reflects tumor immunophenotyping and affects immunotherapy efficiency. This review summarized current studies on the characteristic of tumor immune microenvironment in PCS and discussed the potential of immunotherapy combined with other regimes strategy as a candidate for treatments in PCS.

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