2019 novel coronavirus patients' clinical characteristics, discharge rate and fatality rate of meta-analysis

Long-Quan Li, Tian Huang, Yong-Qing Wang, Zheng-Ping Wang, Yuan Liang, Tao-Bi Huang, Hui-Yun Zhang, Wei-Ming Sun, Yu-Ping Wang
Journal of Medical Virology 2020 March 12

BACKGROUND: To study the clinical data, discharge rate, and fatality rate of COVID-19 patients for clinical help.

METHODS: The clinical data of COVID-19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID-19 patients and explained the discharge rate, fatality rate with a single-arm meta-analysis.

RESULTS: The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), dyspnea (21.9%). Minor symptoms include headache or dizziness: (12.1%) diarrhea (4.8%), nausea, and vomiting (3.9%). The results of laboratory results showed that the lymphocytopenia (64.5%), increase of CRP (44.3%), increase of LDH (28.3%), and leukocytopenia (29.4%) were more common.

CONCLUSIONS: The results of single-arm meta-analysis showed that: the male took a larger percentage in the gender distribution of COVID-19 patients 60%[95%CI (0.54,0.65)], the discharge rate of COVID-19 patients was 42%[95%CI (0.29,0.55)], and the fatality rate was 7%[95%CI (0.04,0.10)]. This article is protected by copyright. All rights reserved.

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