Management of Acute and Recurrent Pericarditis: JACC State-of-the-Art Review

Juan Guido Chiabrando, Aldo Bonaventura, Alessandra Vecchié, George F Wohlford, Adolfo G Mauro, Jennifer H Jordan, John D Grizzard, Fabrizio Montecucco, Daniel Horacio Berrocal, Antonio Brucato, Massimo Imazio, Antonio Abbate
Journal of the American College of Cardiology 2020 January 7, 75 (1): 76-92
Pericarditis refers to the inflammation of the pericardial layers, resulting from a variety of stimuli triggering a stereotyped immune response, and characterized by chest pain associated often with peculiar electrocardiographic changes and, at times, accompanied by pericardial effusion. Acute pericarditis is generally self-limited and not life-threatening; yet, it may cause significant short-term disability, be complicated by either a large pericardial effusion or tamponade, and carry a significant risk of recurrence. The mainstay of treatment of pericarditis is represented by anti-inflammatory drugs. Anti-inflammatory treatments vary, however, in both effectiveness and side-effect profile. The objective of this review is to summarize the up-to-date management of acute and recurrent pericarditis.

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