Diagnosis and Therapy Before Assisted Reproductive Treatments. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Register Number 015-085, February 2019) - Part 1, Basic Assessment of the Woman

Bettina Toth, Dunja Maria Baston-Büst, Hermann M Behre, Alexandra Bielfeld, Michael Bohlmann, Kai Bühling, Ralf Dittrich, Maren Goeckenjan, Katharina Hancke, Sabine Kliesch, Frank-Michael Köhn, Jan Krüssel, Ruben Kuon, Jana Liebenthron, Frank Nawroth, Verena Nordhoff, Germar-Michael Pinggera, Nina Rogenhofer, Sabine Rudnik-Schöneborn, Hans-Christian Schuppe, Andreas Schüring, Vanadin Seifert-Klauss, Thomas Strowitzki, Frank Tüttelmann, Kilian Vomstein, Ludwig Wildt, Tewes Wischmann, Dorothea Wunder, Johannes Zschocke
Geburtshilfe und Frauenheilkunde 2019, 79 (12): 1278-1292
Introduction Supporting and counselling couples with fertility issues prior to starting ART is a multidisciplinary diagnostic and therapeutic challenge. The first German/Austrian/Swiss interdisciplinary S2k guideline on "Diagnosis and Therapy Before Assisted Reproductive Treatments (ART)" was published in February 2019. This guideline was developed in the context of the guidelines program of the German Society of Gynecology and Obstetrics (DGGG) in cooperation with the Swiss Society of Gynecology and Obstetrics (SGGG) and the Austrian Society of Gynecology and Obstetrics (OEGGG). Aims One third of the causes of involuntary childlessness are still unclear, even if the woman or man have numerous possible risk factors. Because the topic is still very much taboo, couples may be socially isolated and often only present quite late to a fertility center. At present, there is no standard treatment concept, as currently no standard multidisciplinary procedures exist for the diagnostic workup and treatment of infertility. The aim of this guideline is to provide physicians with evidence-based recommendations for counselling, diagnostic workup and treatment. Methods This S2k guideline was developed on behalf of the Guidelines Commission of the DGGG by representative members from different professional medical organizations and societies using a structured consensus process. Recommendations The first part of this guideline focuses on the basic assessment of affected women, including standard anatomical and endocrinological diagnostic procedures and examinations into any potential infections. Other areas addressed in this guideline are the immunological workup with an evaluation of the patient's vaccination status, an evaluation of psychological factors, and the collection of data relating to other relevant factors affecting infertility. The second part will focus on explanations of diagnostic procedures compiled in collaboration with specialists from other medical specialties such as andrologists, human geneticists and oncologists.

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