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Benzoazacrown compound: a highly effective chelator for therapeutic bismuth radioisotopes.

MedChemComm 2019 September 2
A new benzoazacrown ligand H4 BATA was synthesized and its complexation ability towards bismuth cations was evaluated. Binding of cation occurs at room temperature in a few minutes and formed complex exhibits the same level of inertness as highly stable complex with the well-known H4 DOTA in biologically relevant and challenging media under in vivo conditions.

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