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Reply to: "The decreasing predictive power of MELD in an era of changing etiology of liver disease".

We read with interest the recent article by Godfrey et al.(1) regarding the predictive power of the Model for End-Stage Liver Disease (MELD), the score used for allocation of donor livers, over time. The authors report that the discriminative ability of MELD for the prediction of 90-day waitlist mortality, as measured by the concordance statistic (c-statistic), had declined from 0.80 in 2002 to 0.70 in 2015 among new waitlist registrants. These values are inconsistent with previously published estimates.

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