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Bivalent AMPA receptor positive allosteric modulators of the bis(pyrimidine) series.

MedChemComm 2019 September 2
The first example of a novel class of AMPA receptor positive allosteric modulators of the bis(pyrimidine) series having a hydroquinone linker has been obtained and showed a potency to increase kainate-induced currents at subnanomolar concentrations.

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