Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants

Anna-My Lund, Chatarina Löfqvist, Aldina Pivodic, Pia Lundgren, Anna-Lena Hård, Ann Hellström, Ingrid Hansen-Pupp
Acta Paediatrica 2019 November 20

AIM: Extrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) were associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants.

METHODS: Observational study of 90 preterm infants born 2013-2015 in Gothenburg, Sweden. Data were prospectively collected on nutritional and breast milk intakes during the first 28 days.

RESULTS: Ninety infants (39 girls and 51 boys) with a median gestational age of 25.3 (22.7-27.9) weeks were evaluated. MM intake (ml/kg/d) correlated positively with almost all z-scores for weight, length, and head circumference at 28 postnatal days and at postmenstrual age (PMA) 32 and 36 weeks. After multivariable adjustment, MM intake and weight z-score at 28 postnatal days and at PMA 32 and 36 weeks remained significantly associated. Infants consuming ≥80% MM had more favourable weight z-scores at PMA 32 and 36 weeks. Intake of DM did not correlate with any growth outcomes. Infants without retinopathy of prematurity had a significantly higher intake of MM (ml/kg/d).

CONCLUSION: Unpasteurised MM was positively associated to longitudinal growth outcomes. Motivating mothers to provide their infants with their own milk after preterm birth should be emphasised.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"