JOURNAL ARTICLE
REVIEW

Management of the Patient with Chronic Intestinal Pseudo-Obstruction and Intestinal Failure

Loris Pironi, Anna Simona Sasdelli
Gastroenterology Clinics of North America 2019, 48 (4): 513-524
31668180
Chronic intestinal pseudo-obstruction (CIPO) is a severe form of intestinal dysmotility disorder, characterized by the impairment of gastrointestinal propulsion of the gut content in the absence of fixed occluding lesions. CIPO is a rare disease that can develop in both children and adults. CIPO is classified as primary/idiopathic, when no underlying disorder is demonstrated, or secondary, when related to systemic diseases. Diagnosis relies on the finding of chronic/recurrent obstructive type symptoms with radiological features of dilated intestine with air/fluid levels without any lumen occluding lesion. Therapy is based on nutrition, pharmacologic and surgical intervention and requires a multidisciplinary approach.

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