Skin lesions and vancomycin use in a hemodialysis patient

Juliet Schurder, Pauline Morel, Julie Blanc, Maëva Clerté, Christophe Ridel, Maxime Touzot
Hemodialysis International 2019, 23 (4): E127-E129
Vancomycin is a widely used antibiotic in hemodialysis patients. The main complications include renal toxicity and skin lesions. Herein, we report the case of a 29-year-old hemodialysis patient who presented a bullous pruriginous dermatosis after vancomycin treatment. A skin biopsy revealed a linear IgA bullous dermatosis (LABD). This is a rare form of dermatosis and is either idiopathic or more likely vancomycin-induced. Similarities in the molecular structure of vancomycin and epidermal basement membrane glycoproteins could explain the auto-immune response. The overall prognosis after drug discontinuation and dermocorticoid treatment was good.

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