JOURNAL ARTICLE

[Hepatic dysfunction in patients with cardiogenic shock]

Philipp Kasper, Frank Tacke, Hans-Michael Steffen, Guido Michels
Medizinische Klinik, Intensivmedizin und Notfallmedizin 2019 September 19
31538212
Cardiogenic shock is a life-threatening condition that is frequently associated with acute hepatic dysfunction. Due to low cardiac output resulting in end-organ hypoperfusion and hypoxia, different types of liver dysfunction can develop, such as hypoxic hepatitis or acute liver failure. A very serious and late sequela is the secondary sclerosing cholangitis in critically patients. Clinical management of acute hepatic dysfunction involves the stabilization of cardiac output to improve hepatic perfusion and the optimization of liver oxygenation. However, despite maximum efforts in supportive treatment, the outcome of patients with cardiogenic shock and concomitant hepatic dysfunction remains poor.

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