Transfusion-related Acute Lung Injury in the Perioperative Patient

Mark J McVey, Rick Kapur, Christine Cserti-Gazdewich, John W Semple, Keyvan Karkouti, Wolfgang M Kuebler
Anesthesiology 2019, 131 (3): 693-715
Transfusion-related acute lung injury is a leading cause of death associated with the use of blood products. Transfusion-related acute lung injury is a diagnosis of exclusion which can be difficult to identify during surgery amid the various physiologic and pathophysiologic changes associated with the perioperative period. As anesthesiologists supervise delivery of a large portion of inpatient prescribed blood products, and since the incidence of transfusion-related acute lung injury in the perioperative patient is higher than in nonsurgical patients, anesthesiologists need to consider transfusion-related acute lung injury in the perioperative setting, identify at-risk patients, recognize early signs of transfusion-related acute lung injury, and have established strategies for its prevention and treatment.


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