Electrocardiogram signal generation using electrical model of cardiac cell: application in cardiac ischemia

Alireza Fallahi, Hamidreza Ghanbari Khorram, Alireza Kokabi
Journal of Medical Engineering & Technology 2019 July 29, : 1-10
One of the most common causes of heart failure is ischaemia. In this disease, the heart muscles die due to the lack or insufficiency of the blood in the cardiac veins. As a result of such a phenomenon, the action potential in that part of the heart would fade. In this article, using the electric model of the cardiac cell and the mechanism of producing an ECG signal in the heart, the process of producing cardiac electrical potential has been modelled. In this regard, the basic constituent signals of the ECG are generated. Afterward, by accumulating these signals, the final ECG is reproduced. In addition, by variation of the presented model parameters, the cardiac ischaemic signal is simulated in a way that the influence of ventricle ischaemia on the ventricular tissues is considered. The results of such a simulation demonstrate a sufficient match between the model output and the reported changes of the cardiac arrhythmia including ischaemic failures. Here, we report the 91% match between the simulated signal and the considered clinical data.


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Available on the App Store

Available on the Play Store
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"