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Melanotic Schwannoma of the Vagina: A Report of a Very Rare Tumor and Review of the Literature

Kofi Effah, Stefan Seidl, Edith Gorges, Patrick Kafui Akakpo
Case Reports in Obstetrics and Gynecology 2019, 2019: 8521834
31316847
Melanotic schwannoma (MS) is a rare nerve sheath tumor with fewer than 200 cases reported. MS has uncertain malignant potential and comprises 1% of all nerve sheath tumors with a predilection for the spinal nerve roots. An even rarer location for this tumor is the vagina. Up to 55% of MSs that contain psammoma bodies are associated with the Carney complex, an autosomal dominant syndrome. Criteria for malignancy in MS are still not well established and long term follow-up of patients is recommended. A 26-year-old woman presented with a bleeding vaginal tumor which was diagnosed as MS following excision. The clinical, histopathological, and immunohistochemical features of this tumor are discussed.

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