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8-Day Inpatient Directly Observed Therapy for ART Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support.

Among 20 highly treatment experienced people with HIV with extensive antiretroviral drug resistance and high levels of self-reported adherence, an inpatient 8-day directly observed therapy confirmed nonadherence as the major cause of virologic failure for 9/20 (45%) participants, preventing unnecessary regimen changes that could jeopardize future treatment options.

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