JOURNAL ARTICLE

[Cirrhotic cardiomyopathy-associated acute cardiac failure in a patient with decompensated alcoholic cirrhosis with massive hepatic hydrothorax]

Yuri Harayama, Kazuhiko Morii, Mutsuko Kuribayashi, Ryunosuke Takechi, Shogo Yonehara, Kazuya Matsumoto, Takuro Masuda, Takeharu Yamamoto, Shinichiro Nakamura, Hiroaki Okushin
Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology 2019, 116 (7): 607-616
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Cirrhotic cardiomyopathy (CCM) is a chronic cardiac dysfunction in patients with cirrhosis and is characterized by altered diastolic relaxation, blunted contractile response to stress, and electrophysiological abnormalities;however, causes of CCM are unknown. Moreover, reduced cardiac afterload due to cirrhosis-related vasodilatation often masks cardiac insufficiency, whereas rapid hemodynamic overload reveals the presence of cirrhotic cardiomyopathy. Herein, we present the case of previously unrecognized cirrhotic cardiomyopathy that became overt with the development of severe acute cardiac failure. The rapidly worsening hepatic hydrothorax increased cardiac preload and intrathoracic pressure, which impaired cardiac filling. Furthermore, cardiac contractile function might have been worsened by hypoxia due to passive atelectasis and concomitant anemia.

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