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Directly Reprogrammed Neurons Still Have Some Growing Up to Do.

Yichen Li, Justin K Ichida
Cell Stem Cell 2019 July 4
Direct lineage conversion offers a fast and simple method to study mature neurons in vitro, but its utility for investigating neurodevelopment has remained unclear. In this issue of Cell Stem Cell, Chanda et al. (2019) use Ngn2-induced neurons to elucidate the pathogenic mechanisms of the teratogenic compound valproic acid.

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