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Research Support, Non-U.S. Gov't
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Direct Ras G12C inhibitors: crossing the rubicon.

Colin R Lindsay, Fiona H Blackhall
British Journal of Cancer 2019 July
Despite its status as the most commonly mutated oncogene in cancer, Ras has long been considered 'undruggable'. In 2019, we will see the first clinical trial results for direct mutant Ras inhibitors, a result of persistent cross-disciplinary research that has been informed by a number of previous clinical and biological failures.

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