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Non-invasive stroke volume estimation by transthoracic electrical bioimpedance versus Doppler echocardiography in healthy volunteers

Mirae Harford, Samuel H Clark, Jodie F Smythe, Stephen Gerry, Mauricio Villarroel, Joao Jorge, Sitthichok Chaichulee, Lionel Tarassenko, Duncan Young, Peter Watkinson
Journal of Medical Engineering & Technology 2019 April 15, : 1-5
Thoracic electrical bioimpedance (TEB) and transthoracic echocardiography (TTE) are non-invasive methods to estimate stroke volume (SV) and cardiac output (CO). Thoracic electrical bioimpedance is not in widespread clinical use with reports of inaccurate cardiac output estimation compared to invasive monitors, particularly in non-healthy populations. We explore its use as a trend monitor by comparing it against thoracic echocardiography in fifteen healthy volunteers undergoing two physical challenges designed to vary cardiac output. Of all paired values, 54.6% showed gross trend agreement and only 1.9% showed direct disagreement between the two monitors. Our results show thoracic bioimpedance may have a role as a non-invasive cardiac output trend monitor in healthy volunteer studies.


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