Cephalosporin-induced linear IgA dermatosis in a child: case report and literature review

S Sarikaya Solak, S Ficicioglu
Dermatologic Therapy 2019 April 12, : e12927
Linear IgA dermatosis (LAD) is a rare, subepidermal blistering disease with mucocutaneous involvement. It may be idiopathic or drug induced. We describe a 4-year-old girl who presented with a vesiculobullous eruption after she had been treated with cefixime for urinary tract infection. A diagnosis of drug-induced LAD was made based on clinical, histopathological and immunofluorescence findings. Naranjo adverse drug reaction algorithm was used to assess imputability resulting with a "probable" association. In literature cephalosporin antibiotics are rarely reported in association with LAD. To our knowledge, this is the first case of a cefixime induced LAD among adults and children. This article is protected by copyright. All rights reserved.

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