Polymer Microarrays for the Discovery and Optimization of Robust Optical Fibre-based pH Sensors.

Polymer microarrays were utilized for the high-throughput screening and discovery of optimal polymeric substrates capable of trapping functional ratiometric fluorescence-based pH sensors. This lead to the identification of poly (methyl methacrylate-co-2-(dimethylamino) ethyl acrylate) (PA101) that allowed, via dip coating, the attachment of fluorescent pH sensors onto the tip of optical fibres that exhibited robust, rapid and reproducible sensing of physiological pH's.