MENU ▼
Read by QxMD icon Read
search
OPEN IN READ APP
JOURNAL ARTICLE

Electrospun PCL-Protein Scaffolds Coated by Pyrrole Plasma Polymerization

Yeyzon Cruz, Efrén Muñoz, E Y Gomez-Pachón, Juan Morales-Corona, Jesús Olayo-Lortia, R Olayo, Roberto Olayo-Valles
Journal of Biomaterials Science. Polymer Edition 2019 April 4, : 1-10
30943867
Polymeric scaffolds prepared from polycaprolactone (PCL), PCL-collagen and PCL-elastin were prepared by electrospinning. The scaffolds were coated by plasma polymerization of pyrrole doped with iodine, to improve cellular adhesion and fibroblast proliferation. The morphology, composition, and crystalline structure of the scaffolds were characterized by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy, small- and wide-angle X-ray scattering, thermogravimetric analysis and differential scanning calorimetry. The scaffold fibers had average diameters between 90 and 330 nm before coating. After coating by plasma polymerization, the average diameters increased to between 290 and 530 nm. The presence of elastin and collagen in the fibers was corroborated by infrared spectroscopy. X-ray scattering measurements show that neither elastin nor collagen form crystals in the fiber, while PCL maintains its crystallinity and is not affected by the plasma treatment. Fibroblast cell cultures in the presence of the scaffolds were characterized by viability assays and SEM. The results show that the scaffolds modified with plasma polymerized pyrrole provide a suitable environment for fibroblast adhesion, growth and viability.

Comments

You need to log in or sign up for an account to be able to comment.

No comments yet, be the first to post one!

Related Papers

Available on the App Store

Available on the Play Store
Remove bar
Read by QxMD icon Read
30943867
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"