JOURNAL ARTICLE
REVIEW
Add like
Add dislike
Add to saved papers

Shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage.

INTRODUCTION: Shunt-dependent hydrocephalus (SDHC) after aneurysmal subarachnoid hemorrhage (aSAH) is the occurrence of symptomatic ventriculomegaly requiring permanent shunt diversion. Although several studies investigated the predictors of SDHC, the role of many of these factors, as well as the prevalence of SDHC and patients' clinical outcome, remain a matter of controversy.

EVIDENCE ACQUISITION: According to PRISMA guidelines we performed a systematic search looking into four databases with the purpose of clarifying the prevalence of SDHC after aSAH, the predictors of SDHC, the mortality rate and clinical outcome of patients with and without SDHC.

EVIDENCE SYNTHESIS: Our analysis included 23 studies involving 22,264 patients. The overall prevalence of SDHC was 22.3% (95% CI: 17.9-26.6%). The predictors of SDHC included radiological hydrocephalus at presentation (OR 6.3, 95% CI: 2.27-17.51%), external ventricular drainage insertion (OR 5.7, 95% CI: 3.77-8.61%), high Hunt and Hess scale score (HHS 3-5: OR 3.3, 95% CI: 2.64-4.15%; HHS 4-5: OR 3.2, 95% CI: 2.4-4.2%), high Fisher grade (OR 3.1, 95% CI: 2.58-3.72%), intraventricular blood (OR 3.1, 95% CI: 2.60-3.71%), vasospasm (OR 1.9, 95% CI: 1.30-2.81%), intraparenchymal hemorrhage (OR 1.8, 95% CI: 1.2-2.78%), female gender (OR 1.3, 95% CI: 1.14-1.65%) and posterior circulation aneurysms (OR 1.4, 95% CI: 1.11-1.71%). The modality of aneurysm repair did not affect the rate of permanent shunt diversion. Patients with SDHC were more likely to be associated with a poor clinical outcome (mRS 3-6) (OR 4.3), even if mortality rate was similar between shunted and non-shunted patients (9%, 95% CI: 2-16% vs. 10.8%, 95% CI: 3.2-18.5%) (P=0.09).

CONCLUSIONS: The prevalence of SDHC is 22.3%. Our analysis identified several predictors of SDHC that can assist clinicians in monitoring patients with an aSAH. Shunt dependency is not related to the treatment modality of the ruptured aneurysm, whereas the occurrence of SDHC is a predictor of poor clinical outcome.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app