Are certain factors involved in calcium metabolism associated with temporomandibular disorders?

Azamsadat Madani, Seyed Aliakbar Shamsian, Parvin Layegh, Seyyed Mohammad Abrisham, Ali Ravaghi, Niloufar Tayarani Najjaran
Cranio: the Journal of Craniomandibular Practice 2019 March 31, : 1-7

OBJECTIVE: The aim of the present study was to investigate whether there is an association between serum concentrations of calcium, phosphate, alkaline phosphatase, parathyroid hormone (PTH), and vitamin D and temporomandibular disorders (TMDs).

METHODS: In this case-control study, 51 patients with TMDs (28 patients with TMJ clicking, 5 patients with muscular disorders, and 18 osteoarthritis patients) and 29 healthy subjects within the age range of 20-50 years as the control group, were referred to the laboratory for calcium, phosphate, alkaline phosphatase, PTH, and vitamin D (25 OHD) analysis tests. The TMJ status of all participants was examined according to RDC-TMD criteria by a prosthodontist who is an expert in TMDs. The results were analyzed with Fisher's precise test.

RESULTS: No statistically significant difference was observed between TMD patients and healthy subjects.

CONCLUSION: Serum concentrations of calcium, phosphate, alkaline phosphatase, PTH, and vitamin D are not associated with TMDs.

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