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JOURNAL ARTICLE
REVIEW

The role of ocular dendritic cells in uveitis

Wei Lin, Tingting Liu, Beibei Wang, Hongsheng Bi
Immunology Letters 2019 March 26
30926373
Dendritic cells (DCs) act as a bridge between innate and adoptive immunity. They are widely distributed in various tissues and organs. Resident ocular DCs are found in the peripheral margins and juxtapapillary areas of the retina, usually in an immature state. During inflammation, DCs are activated and participate in the development of uveitis, an ocular inflammatory disease. Herein, the characteristics and status of DCs in uveitis, the possible factors affecting the status of DCs, and the clinical methods for detecting the DCs in patients are described.

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