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Prevalence and Risk Factors for Metabolic Syndrome among Hypertensive Patients Attending the General Outpatient Clinic of a Tertiary Hospital in North Central Nigeria.

BACKGROUND: Metabolic syndrome is an important cause of morbidity and mortality. It is important to identify those at risk and initiate early interventions to prevent or delay its onset and complications.

METHODS: It was a hospital-based descriptive cross-sectional study conducted from 1 September to 31 October, 2014. One hundred and ninety one adult hypertensive patients were recruited from the General Outpatients Clinic using a convenience sampling technique in which participants randomly picked folded papers numbered 1-10 daily. Those who picked even numbers were recruited into the study. Data about socio-demographic characteristics, lifestyle, history of hypertension and co-morbidities were collected using a pre-tested interviewer-administered questionnaire. Physical examination included blood pressure, body mass index (BMI), waist circumference and waist:hip ratio (WHR). Laboratory indices included fasting blood glucose and lipid profile. Metabolic syndrome was diagnosed based on the USA National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) definition. Approval for the study was obtained from the Research Ethics Committee of Dalhatu Araf Specialist Hospital, Lafia on 19 June 2014. (No. DASH/I/ADM/0340).

RESULTS: There were 36 (19.8%) males and 146 (80.2%) females, with a mean age of 50.3 + 10.7 years. The prevalence of metabolic syndrome was 32.4%. The commonest pattern was the combination of hypertension, abdominal obesity and hypertriglyceridaemia in 25 (13.7%) participants. Logistic regression analysis showed that physical activity is protective against metabolic syndrome (OR = 0.072, 95% CI = 0.009 - 0.571, p = 0.013) while large waist circumference (abdominal obesity) is associated with an increased risk for metabolic syndrome (OR = 9.986, 95% CI = 3.689 - 27.030, p = 0.000).

CONCLUSION: Metabolic syndrome is common in hypertensive patients in the study area. Physicians should screen all patients with hypertension for early identification of those at greater risk of metabolic syndrome.

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