Phyllodes tumor with a benign heterologous osseous component: A diagnostic challenge.

Phyllodes tumors (PTs) are uncommon fibroepithelial neoplasms that account for 0.3-1% of all primary breast tumors and for 2,5% of all fibroepithelial tumors of the breast in "Western" countries 1, 2. The median age at diagnosis is about 45 years. In Asian countries the median age at diagnosis is 25-30 years, and PTs account for a higher proportion of breast tumors 2. PTs are characterized by a combination of an expanding hypercellular stroma with enhanced intracanalicular growth pattern with leaf-like projections into irregular, elongated epithelial-lined clefts. The epithelial component consists of a well differentiated luminal epithelialcell layer surrounded by a layer of myoepithelial cells. Great morphological variations can however be seen 2-4. This article is protected by copyright. All rights reserved.