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Preface to COAST 2018 Innovators' Workshop: Bridging the biology and technology gap in orthodontics and craniofacial care.

AUTHORS: Iwasaki LR, Covell DA Jr, Frazier-Bowers SA, Huja SS, Kapila S, Nickel JC.

OBJECTIVE: A third focused workshop explored how to transfer novel findings into clinical orthodontic practice.

SETTING AND SAMPLE POPULATION: Participants met at the Scottsdale Plaza Resort, September 12-16, 2018 for the Consortium for Orthodontic Advances in Science and Technology 2018 Innovators' Workshop. Thirty speakers and four lunch-hour focus group leaders shared and exchanged information with approximately 45 registered attendees.

MATERIAL AND METHODS: This Innovators' Workshop was organized according to five themed sessions which covered: 1. The relevance of genetics, biology and environment to therapeutic outcomes; 2. Application of bioinformatics in craniofacial research; 3. Regeneration with and for orthodontic treatment; 4. Technology in precision orthodontics; and 5. Muscle, joint, and airway: Growth, function and pain.

RESULTS: The papers that comprise this supplemental issue exemplify the important outcomes of the 2018 COAST Workshop. In addition, matters identified as important needs include: Improved understanding of neural, skeletal and muscle tissue crosstalk in early craniofacial growth; standardized methods for three-dimensional radiographic and surface landmark and reference plane identification, measurements, and serial superimpositioning techniques for use in the clinic; sharing and making available existing data sets (e.g., cone beam computed tomography images, genotype-phenotype data); evidence of the usefulness and effectiveness of new devices; guidelines of what to measure to characterize the airway; more information about the influences of the soft tissues on craniofacial morphology; and information about effective digital work flows applied to clinical and educational settings.

CONCLUSIONS: Progress in bridging the biology-technology gap has identified new needs for improvements in orthodontics and craniofacial care. This article is protected by copyright. All rights reserved.

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