Expanding the Spectrum of Light-Driven Peroxygenase Reactions.

Peroxygenases require a controlled supply of H2 O2 to operate efficiently. Here, we propose a photocatalytic system for the reductive activation of ambient O2 to produce H2 O2 which uses the energy provided by visible light more efficiently based on the combination of wavelength-complementary photosensitizers. This approach was coupled to an enzymatic system to make formate available as a sacrificial electron donor. The scope and current limitations of this approach are reported and discussed.