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Bacterial Mix Enhances Immunotherapy Response.
Cancer Discovery 2019 Februrary 16
Researchers have isolated a mix of 11 strains of bacteria that increase the effectiveness of checkpoint inhibitors in mice. The bacteria boosted IFNγ+ CD8+ T-cell counts and enhanced anti-PD-1 and anti-CTLA4 treatments in mice implanted with colon cancer or melanoma cells, findings that could have implications for patient care.
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