Bridging exosome and liposome through zirconium-phosphate coordination chemistry: a new method for exosome detection.

We have proposed a new exosomes-zirconium-liposomes sandwich structure to detect exosomes by using zirconium-phosphate coordination chemistry. The combined use of the intrinsic property of phosphate in both exosomes and liposomes as well as zirconium ions can endow the method lower cost, no modified label, simplicity and high efficiency.