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We Could Use More Tolerance: Role of Intestinal-Allograft-Derived Human Stem Cells.

Norma Sue Kenyon
Cell Stem Cell 2019 Februrary 8
Mixed chimerism is associated with allograft acceptance and tolerance. In this issue of Cell Stem Cell, Fu et al. (2019) provide evidence that functional, donor-derived hematopoietic stem and progenitor cells in the intestinal allograft can persist long-term, contribute to multi-lineage chimerism in the circulation, and result in T cell tolerance through host lymphoid organ selection.

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