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Phenylpropanoids, flavonoids and terpenoids from Artemisia ordosica Krasch.

From the CH2 Cl2 extract of Artemisia ordosica, two new phenylpropanoids, ordosicin A (9) and ordosicin B (10), was obtained in addition to two known phenylpropanoids [dihydroconiferyl alcohol (3) and coniferyl alcohol (4)]. Moreover, five flavonoids [5-hydroxy-7,4'-dimethoxyflavanone (5), 3,5-dihydroxy-7,4'-dimethoxyflavone (6), 5,4'-dihydroxy-7-methoxyflavanone (7), 5,4'-dihydroxy-7,3'-dimethoxyflavanone (8) and acacetin (11)] and two terpenoids [spathulenol (1) and uvaol (2)] were isolated and identified. The structures of new compounds were elucidated on the basis of spectroscopic methods including UV, IR, ESI-MS, 1D NMR and 2D NMR. Antioxidant activity of the CH2 Cl2 crude extract, fractions and new compounds were evaluated for their radical scavenging capacity using 2,2-diphenyl-1-picryhydrazyl (DPPH). The crude extract, fraction 3, the new compounds namely ordosicin A (9) and ordosicin B (10) exhibited significant antioxidant activity.

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