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Letrozole and Unexplained Infertility: A Contemporary Meta-analysis.

The results of a meta-analysis comparing the efficacy of clomiphene versus letrozole among couples with unexplained infertility in 2014 are in contrast to those of a randomized trial in 2015. This new meta-analysis included randomized studies that were not previously included and found that the efficacy of clomiphene or letrozole in women with unexplained infertility is comparable (Canadian Task Force Classification I).

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